NIGEB | Engineering a productive & safe life
National Institute of Genetic Engineering and Biotechnology

Engineering a
Productive & Safe Life

Explore research opportunities, international joint projects, qualified education, and elite fellowships with national and global impact at NIGEB.

Research & Education ICGEB Opportunities

Latest achievements

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LATEST RELEASE • APR 2026

Unraveling stress-adaptation pathways in cancer: Functional dissection through CRISPR-based genetic screens

Utilized genome-wide CRISPR/Cas9 screens in glioblastoma cells to identify ZNRF3 and other genes as key regulators in adapting to glucose restriction within the tumor microenvironment.

LATEST RELEASE • MAR 2026

Design and structural characterization of a chimeric protein displayed on virus-like particles for targeted immune activation against Salmonella Typhi

Designed a highly stable VLP-based chimeric vaccine named NanosalVAX, conferring 100% protection against lethal bacterial challenges in preclinical animal models.

LATEST RELEASE • APR 2026

An In Silico-Designed Chimeric Antigen Confers Broad Protection Against Major Diarrheal Pathogens

Engineered a polyvalent chimeric antigen termed "SEISL" capable of simultaneously combating three major bacterial families responsible for life-threatening diarrheal infections.

LATEST RELEASE • FEB 2026

Encapsulation of hydroxyurea in exosomes derived from adipose mesenchymal stem cells enhances anticancer efficacy in breast cancer

Leveraged AD-MSC derived natural nanocarriers to target breast cancer cells, significantly reducing the required drug dosage while effectively bypassing resistance mechanisms.

LATEST RELEASE • APR 2026

Aspirin alters molecular crosstalk between prostaglandin, apoptosis, and invasion pathways in colorectal cancer

Decoded how aspirin disrupts post-transcriptional networks, severing the link between PTGS2 expression and the aggressive MMP-9 invasion protein in clinical tumor samples.

Announcements

Wars and Biosphere Symposium SEP 2026

Wars and Biosphere Symposium : Investigating the Ecological Warfare Impact Scheduled for September 2026

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Agriculture Industrial and Environmental Medical Users

Ecosystem of Innovation

A decentralized network of top-tier facilities, minds, and output driving the biotech revolution globally.

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NIGEB Research Campus

A comprehensive research environment designed to foster collaboration. The campus houses state-of-the-art laboratories, specialized greenhouses, and cross-disciplinary institutes pushing the boundaries of biotechnology.

Resident Company

Science and Technology Campus

In the field of genetic engineering in Iran

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Resident Company

NIGEB

National Institute of Genetic Engineering and Biotechnology

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Plant Bioproducts Facility

National Olive Germplasm

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Documented Iranian olive varieties preserved for genetic analysis and agricultural resilience.

Model Animal Development Center

Advanced facility and animal house dedicated to the breeding, care, and study of transgenic mice, accelerating critical medical and pharmacological research.

Transgenics In-Vivo Studies
Model Animal Development Facility